Table 1.
Baseline characteristics and renal outcome of the untreated hepatitis B virus-infected and hepatitis B virus-uninfected chronic kidney disease patients (n = 103002), 1997-2012
| Variable | Overall CKD patients (n = 103002) |
Propensity score-matched CKD patients (n = 14580) |
||||
| Untreated (n = 2916) | Uninfected (n = 100086) | P value | Untreated (n = 2916) | Uninfected (n = 11664) | P value | |
| Sex | < 0.0001 | 0.45 | ||||
| Men | 1713 (58.7) | 51592 (51.6) | 1713 (58.7) | 6762 (58.0) | ||
| Women | 1203 (41.3) | 48494 (48.4) | 1203 (41.3) | 4902 (42.0) | ||
| Age (yr, mean ± SD) | 48.1 ± 14.4 | 56.3 ± 17.4 | < 0.0001 | 48.1 ± 14.4 | 47.7 ± 15.9 | 0.21 |
| Comorbidity | ||||||
| Diabetes | 749 (25.7) | 33023 (33.0) | < 0.0001 | 749 (25.7) | 3049 (26.1) | 0.62 |
| Hypertension | 884 (30.3) | 45139 (45.1) | < 0.0001 | 884 (30.3) | 3420 (29.3) | 0.29 |
| Coronary heart disease | 316 (10.8) | 18668 (18.7) | < 0.0001 | 316 (10.8) | 1152 (9.9) | 0.12 |
| Hyperlipidemia | 695 (23.8) | 29595 (29.6) | < 0.0001 | 695 (23.8) | 2851 (24.4) | 0.49 |
| Cirrhosis | 139 (4.8) | 1528 (1.5) | < 0.0001 | 139 (4.8) | 472 (4.1) | 0.08 |
| Urbanization level | 0.0003 | 0.47 | ||||
| Urban | 892 (30.6) | 27951 (27.9) | 892 (30.6) | 3595 (30.8) | ||
| Suburban | 1351 (46.3) | 46163 (46.1) | 1351 (46.3) | 5498 (47.2) | ||
| Rural | 673 (23.1) | 25972 (26.0) | 673 (23.1) | 2571 (22.0) | ||
| Enrolee category | < 0.0001 | 0.011 | ||||
| 1 + 2 | 1122 (38.5) | 29935 (29.9) | 1122 (38.5) | 4680 (40.1) | ||
| 3 | 1278 (43.8) | 47825 (47.8) | 1278 (43.8) | 4760 (40.8) | ||
| 4 | 516 (17.7) | 22326 (22.3) | 516 (17.7) | 2224 (19.1) | ||
| No. of medical visits (mean ± SD) | 26.1 ± 20.8 | 29.0 ± 22.8 | < 0.0001 | 26.1 ± 20.8 | 25.7 ± 22.5 | 0.31 |
| Charlson comorbidity index score (mean ± SD) | 1.6 ± 1.9 | 1.9 ± 2.3 | < 0.0001 | 1.6 ± 1.9 | 1.5 ± 2.1 | 0.06 |
| Propensity score (mean ± SD) | 0.4 ± 0.2 | 0.3 ± 0.2 | < 0.0001 | 0.4 ± 0.2 | 0.4 ± 0.2 | 1.00 |
| End-stage renal disease | ||||||
| Follow-up year (mean ± SD) | 8.9 ± 3.9 | 6.9 ± 4.5 | < 0.0001 | 8.9 ± 3.9 | 7.4 ± 4.5 | < 0.0001 |
| Total follow-up (person-year) | 26098 | 689592 | < 0.0001 | 26098 | 86780 | < 0.0001 |
| Event | 197 (6.8) | 4076 (4.1) | < 0.0001 | 197 (6.8) | 414 (3.6) | < 0.0001 |
Categorical variables are given as n (%); continuous variable given as mean ± SD. CKD: Chronic kidney disease.