Table 1.
UC | CD | UIBD | Total | |
No. of patients (n) | 39 (17.8) | 176 (80.4) | 4 (1.8) | 219 |
Age in yr | 42.74 ± 13.60 | 30.51 ± 11.84 | 45.25 ± 16.62 | 33.44 ± 13.08 |
Sex, M/F | 27/12 | 132/44 | 1/3 | 161/59 |
TPMT genotype | ||||
A/A | 38 (97.4) | 174 (98.9) | 4 (100) | 216 (98.6) |
A/Ga | 1 (2.6) | 2 (1.1) | 0 | 3 (1.4) |
NUDT15 genotype | ||||
C/C | 31 (79.5) | 140 (79.5) | 4 (100) | 175 (79.9) |
C/T | 8 (20.5) | 36 (20.5) | 0 | 44 (20.1) |
AZA therapy | 3 (7.7) | 77 (43.8) | 0 | 80 (36.5) |
Data are presented as n (%) or mean ± SD.
P < 0.05 vs NUDT15 C/T. CD: Crohn’s disease; UC: Ulcerative colitis; UIBD: Undetermined inflammatory bowel disease, AZA: Azathioprine.