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. 2018 Feb 27;8:3684. doi: 10.1038/s41598-018-22058-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Reactivity of rheumatoid arthritis and healthy donor sera to selected linear EBNA-2 peptides originating from three Epstein-Barr virus strains anslysed by streptavidin capture ELISA. *Specificity is calculated based on the reactivity of 10 healthy donor sera (HD) to the specific peptides. Statistical calculations are performed using the Student’s t-test, where antibody reactivity to healthy controls is used for comparison. a. Reactivity of rheumatoid arthritis sera (n = 15). b. Reactivity of healthy donor sera (n = 10).