Table 1.
Arg-Gly motifs located in EBNA proteins in three Epstein-Barr virus strains.
| Protein | Sequence | Strain | Strain match | Sequence match* |
|---|---|---|---|---|
| EBNA-2 | MANYIVRQSRGDRGLILPQG | B95-8, GD1 | 2/3 | 100% |
| YIVRQSRGDRGLILPQGPQT | B95-8, GD1 | 2/3 | 100% | |
| QPSKTQGQSRGQSRGRGRGR | B95-8, GD1 | 2/3 | 100% | |
| TQGQSRGQSRGRGRGRGRGR | B95-8, GD1 | 2/3 | 100% | |
| GQSRGQSRGRGRGRGRGRGK | B95-8, GD1 | 2/3 | 100% | |
| SRGQSRGRGRGRGRGRGKGK(B95-8) SRGQSRGRGRGRGRGRGKSR(GD1) |
B95-8, GD1 | 2/3 | 90% | |
| GQSRGRGRGRGRGRGKGKSR(B95-8) GQSRGRGRGRGRGRGKSRDK(GD1) |
B95-8, GD1 | 2/3 | 80% | |
| SRGRGRGRGRGRGKGKSRDK(B95-8) SRGRGRGRGRGRGKSRDKQR(GD1) |
B95-8, GD1 | 2/3 | 70% | |
| GRGRGRGRGRGKGKSRDKQR(B95-8) GRGRGRGRGRGKSRDKQRKP(GD1) |
B95-8, GD1 | 2/3 | 60% | |
| MAQYLLRNARGQQGLLRPLG | AG876 | 1/3 | — | |
| KQGPDQGQGRGRWRGRGRSK | AG876 | 1/3 | — | |
| DQGQGRGRWRGRGRSKGRGR | AG876 | 1/3 | — | |
| GQGRGRWRGRGRSKGRGRMH | AG876 | 1/3 | — | |
| WRGRGRSKGRGRMHKLPEPR | AG876 | 1/3 | — | |
| EBNA-LP | RRHRSPSPTRGGQEPRRVRR | B95-8, GD1, AG876 | 3/3 | 100% |
| VVSGSPSGPRGDRSEGPGPT | B95-8, GD1, AG876 | 3/3 | 100% | |
| EBNA-3A | EDAHLEPSQRGKKRKRVDDD | AG876 | 1/3 | — |
| AQAWNAGFLRGRAYGIDLLR(B95-8) AQAWNAGFLRGRAYGLDLLR(GD1) AQAWNAGLLRGRAYGQDLLR(AG876) |
B95-8, GD1, AG876 | 2/3 1/3 |
GD1: 95% AG876: 90% — |
|
| DQLPGVPKGRGACAPVPALA | AG876 | 1/3 | — | |
| DEDLPCIVSRGGPKVKRPPI | B95-8, GD1 | 2/3 | 100% | |
| QGKEVLEKARGSTYGTPRPP | B95-8, GD1 | 2/3 | 100% | |
| GMAYPLHEQRGMAPCPVAQA | GD1 | 1/3 | — | |
| EBNA-3B | NEEIDLAYARGQAMNIEAPR SEETDLAYARGLAMSIEAAR(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 75% |
| VPPVPRQRPRGAPTPTPPPQ VPPVPRQRPRGAPTPTPPPQ(B95-8) VPPVPRQRSRGAPTPTPPPQ(GD1) GPPTAMQRPRGAPTPMPPPQ(AG876) |
B95-8, GD1 B95-8, GD1, AG876 |
2/3 3/3 |
100% GD1: 95% AG876: 75% |
|
| VPQQPRAGRRGPCVFTGDLG(B95-8) VPQQPQAGRRGPCVYTGDLG(GD1) |
B95-8, GD1 | 2/3 | 90% | |
| APTEYTRERRGVGPMPPTDI(B95-8) EPTEYTRERRGVGPMPPTDI(GD1) |
B95-8, GD1 | 2/3 | 95% | |
| EBNA-3C | DSRQSPDNERGDNVQTTGEH(B95-8) DSIQSPDNARGDDVQNTGEH(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 80% |
| RDQQPWGQSRGDENRGWMQR(B95-8) RDQQSRGQRRGDENRGWMQR(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 85% |
|
| WGQSRGDENRGWMQRIRRRR(B95-8) RGQRRGDENRGWMQRIRRRR(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 90% |
|
| ARQRLQDIRRGPLVVEGGVG(GD1) ARQRLQDIRRGPLVAEGGVG(B95-8) |
GD1, B95-8, AG876 | 3/3 | B95-8:95% AG876:100% |
|
| AREAEVRFLRGKWQRRYRRI(B95-8) AREAEVRFLRGKWQRRFRRI(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 95% |
|
| PNENPYHARRGIKEHVIQNA(B95-8) PNENPYHARRGIKEQVIQKA(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 95% |
|
| SMLATGGEPRGDATSETSSD(B95-8) SMLATVGEPRGDATSETSSD(GD1) SMLATGGGPRGDATSETSSD(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 95% A876: 95% |
|
| PTPPPSRRRRGACVVYDDDV(B95-8) PPPPPSRRRRGACVVYDDDI(AG876) |
B95-8, GD1, AG876 | 3/3 | GD1: 100% AG876: 90% |
|
| EPDSRDQQSRGQRRGDENRG | AG876 | 1/3 | — |
*Sequence match is calculated relative to the listed EBV strain for the specific peptide.