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Genomic gain of catalase locus in breast cancer cell lines is not responsible for catalase overexpression in resistant cells. (a) Karyotypes: chromosome 11 of human normal epithelial cells (250MK) and breast cancer cell lines. (b) Hybridization of catalase (red spots) and control (green spots) FISH probes on metaphases of 250 MK cells. (c) MCF-7 and (d) Resox cells.
