Table 3.
Mean ± SD of exercise capacity and blood chemistry
| Group A (n = 44) | Group B (n = 41) | |||||
| T0 | T6 | T12 | T0 | T6 | T12 | |
| Maximum workload (W) | 95 ± 36 | 107 ± 38a | 108 ± 41c | 102 ± 32 | 102 ± 30 | 98 ± 34 |
| V’O2 peak (mL/kg per minute) | 22.8 ± 8.3 | 25.6 ± 9.0a | 25.9 ± 7.5c | 21.6 ± 6.8 | 22.6 ± 6.6 | 21.5 ± 6.4 |
| HR max (bpm) | 142 ± 24 | 142 ± 22 | 145 ± 22c | 133 ± 22 | 134 ± 23 | 131 ± 22 |
| Diastolic BP at rest (mmHg) | 80 ± 8 | 80 ± 8 | 78 ± 6 | 81 ± 9 | 82 ± 8 | 82 ± 8 |
| Diastolic BP at V’O2 peak (mmHg) | 85 ± 11 | 83 ± 12 | 82 ± 13 | 84 ± 10 | 81 ± 13 | 80 ± 11 |
| Diastolic BP at 3’ recovery (mmHg) | 75 ± 9 | 76 ± 8 | 75 ± 9 | 78 ± 10 | 79 ± 9 | 78 ± 8 |
| Systolic BP at rest (mmHg) | 126 ± 14 | 126 ± 12 | 125 ± 11 | 130 ± 16 | 126 ± 15 | 127 ± 13 |
| Systolic BP at V’O2 peak (mmHg) | 183 ± 26 | 183 ± 21 | 185 ± 25 | 181 ± 26 | 181 ± 27 | 178 ± 30 |
| Systolic BP at 3’ recovery (mmHg) | 128 ± 17 | 129 ± 14 | 131 ± 16 | 136 ± 16 | 136 ± 21 | 135 ± 20 |
| Body mass index (kg/m2) | 24.1 ± 4.3 | 24.0 ± 4.3 | 23.6 ± 4.5c | 25.5 ± 4.4 | 25.3 ± 4.0 | 25.8 ± 4.5 |
| Fat mass (%) | 21.1 ± 9.0 | 19.8 ± 8.3a | 20.7 ± 7.9 | 20.0 ± 7.8 | 18.9 ± 6.5 | 19.8 ± 8.1 |
| Aerobic threshold workload (W) | 53 ± 23 | 60 ± 29 | 60 ± 27 | 53 ± 21 | 62 ± 27 | 57 ± 25 |
| Aerobic threshold HR (bpm) | 113 ± 20 | 108 ± 19 | 112 ± 18 | 103 ± 16 | 103 ± 19 | 103 ± 16 |
| Anaerobic threshold workload (W) | 84 ± 30 | 94 ± 37 | 91 ± 31c | 89 ± 32 | 97 ± 38 | 88 ± 36 |
| Anaerobic threshold HR (bpm) | 131 ± 21 | 130 ± 23 | 134 ± 18c | 125 ± 20 | 125 ± 21 | 120 ± 19e |
| Knee extensors right (kg) | 87 ± 38 | 93 ± 40 | 98 ± 39 | 55 ± 27 | 61 ± 26 | 60 ± 24 |
| Knee extensors left (kg) | 80 ± 36 | 93 ± 40 | 95 ± 42 | 51 ± 23 | 60 ± 25 | 58 ± 23 |
| Plantar flexors right (kg) | 70 ± 34 | 76 ± 29 | 82 ± 27c | 62 ± 35 | 69 ± 27 | 65 ± 23 |
| Plantar flexors left (kg) | 70 ± 33 | 77 ± 29 | 79 ± 28 | 64 ± 34 | 71 ± 24 | 67 ± 24 |
| Counter movement jump (cm) | 24.0 ± 10.0 | 26.4 ± 10.2 | 25.9 ± 9.3c | 21.5 ± 9.4 | 22.9 ± 10.2 | 20.9 ± 10.2 |
| Handgrip right (kg) | 30.8 ± 13.1 | 33.2 ± 12.2 | 32.3 ± 11.9c | 36.3 ± 9.5 | 35.9 ± 9.8 | 34.2 ± 9.6 |
| Handgrip left (kg) | 29.3 ± 13.6 | 30.7 ± 11.7 | 30.6 ± 11.7c | 35.1 ± 9.3 | 34.4 ± 9.7 | 32.7 ± 10.2 |
| Elbow flexors Right (kg) | 8.8 ± 2.7 | 9.4 ± 2.8 | 9.7 ± 2.8 | 8.0 ± 3.4 | 9.4 ± 3.1e | 9.4 ± 3.5 |
| Elbow flexors Left (kg) | 8.7 ± 3.2 | 9.6 ± 3.4 | 9.6 ± 3.1 | 7.3 ± 3.4 | 8.6 ± 2.7e | 8.7 ± 3.5 |
| Elbow extensors right (kg) | 5.8 ± 2.0 | 6.5 ± 2.3 | 6.9 ± 2.3 | 5.1 ± 2.2 | 6.1 ± 2.1e | 6.0 ± 2.1 |
| Elbow extensors left (kg) | 5.7 ± 2.0 | 6.5 ± 2.4 | 6.8 ± 2.4 | 4.9 ± 2.3 | 5.6 ± 1.8e | 5.7 ± 1.9 |
| Shoulder abductors (kg) | 5.3 ± 2.2 | 6.3 ± 2.5 | 6.4 ± 2.3 | 4.2 ± 2.7 | 5.2 ± 2.1e | 5.4 ± 2.7 |
| Creatinine (mg/dL) | 1.26 ± 0.38 | 1.27 ± 0.41 | 1.21 ± 0.29 | 1.37 ± 0.48 | 1.32 ± 0.50 | 1.42 ± 0.47 |
| eGFR (mL/min per 1.73 m2) | 59.4 ± 19.3 | 58.0 ± 19.6 | 62.6 ± 21.8 | 56.3 ± 21.2 | 58.1 ± 17.8 | 52.9 ± 17.4 |
| Proteinuria (g/24 h) | 0.41 ± 0.51 | 0.34 ± 0.46 | 0.52 ± 0.63 | 0.45 ± 0.57 | 0.48 ± 0.59 | 0.61 ± 0.44 |
| Haemoglobin (g/dL) | 12.8 ± 1.8 | 12.3 ± 1.7 | 12.6 ± 1.6 | 12.1 ± 1.8 | 12.5 ± 1.9 | 12.8 ± 1.5 |
| Triglycerides (mg/dL) | 122 ± 42 | 117 ± 41 | 117 ± 47 | 138 ± 69 | 131 ± 57 | 132 ± 59 |
| Cholesterol (mg/dL) | 196 ± 37 | 186 ± 52 | 200 ± 43 | 195 ± 33 | 193 ± 31 | 188 ± 34 |
In Group A:
a
P < 0.05 between T0 and T6,
c
P < 0.05 between T0 and T12; In Group B:
e
P < 0.05 between T0 and T12. BP: Blood pressure; HR: Heart rate; eGFR: Estimated glomerular filtration rate.