Fig. 1.

Ventricular myocytes treated with 0.01% H₂O₂ for 6 hours (left) or doxorubicin for 24 hours (right) result in a 3-fold and 2-fold up-regulation of CYP2J2 expression, respectively. Each experiment was performed in triplicate (nine data points per condition). Data were normalized to vehicle-treated cells (PBS for hydrogen peroxide and 0.1% DMSO for doxorubicin). Significance was determined using unpaired t test. ****P < 0.0001.