Table 1.
Characteristics of groups.
| Control (n = 52) | MWA (n = 52) | MwoA (n = 58) | p-Value MWA vs. control | p-Value MwoA vs. control | |
|---|---|---|---|---|---|
| Age, mean ± SD (years) | 32.2 ± 6.1 | 33.8 ± 7.1 | 33.7 ± 6.7 | 0.20 | 0.20 |
| Female, n (%) | 39 (75) | 45 (87) | 43 (74) | 0.13 | 0.92 |
| Systolic blood pressure, mean ± SD (mm Hg) | 124 ± 16 | 126 ± 19 | 128 ± 19 | 0.51 | 0.26 |
| Diastolic blood pressure, mean ± SD (mm Hg) | 79 ± 9 | 82 ± 13 | 85 ± 13 | 0.17 | 0.02 |
| Hypertension, n (%) | 1 (2) | 2 (4) | 4 (7) | 0.55 | 0.19 |
| Diabetes, n (%) | 0 (0) | 1 (2) | 0 (0) | 0.24 | – |
| Smoker, current or former, n (%) | 11 (21) | 12 (23) | 23 (40) | 0.81 | 0.03 |
| Migraine duration, mean ± SD (years) | 18.9 ± 9.8a | 14.0 ± 8.7 | |||
| Migraine frequency, per month, median (IQR) | 3 (1–5)b | 2 (1–6) | |||
| High white matter hyperintensity burden | 17.3% | 21.1% | 24.1% | 0.62 | 0.38 |
| ≥1 white matter hyperintensity | 23% | 27% | 34% | 0.65 | 0.18 |
| PCA CBF (ml/100 g/min)c | 54.8 ± 14.0 | 55.8 ± 14.5 | 55.8 ± 14.2 | 0.74 | 0.74 |
| Basilar artery diameter, mean, SD (mm) | 3.6 ± 0.6 | 3.6 ± 0.6 | 3.6 ± 0.6 | 0.70 | 0.94 |
| Vertebral artery asymmetry, median, IQR (mm) | 0.3 (0.2–0.8) | 0.5 (0.1–1.0) | 0.6 (0.1–1.1) | 0.47 | 0.27 |
| Basilar artery displacement, mean, SD (mm) | 4.9 ± 3.1 | 6.3 ± 3.8 | 5.1 ± 3.0 | 0.055 | 0.76 |
ap = 0.02 vs. MwoA.
bp = 0.61 vs. MwoA.
cPerfusion data were available for 149 of the subjects (47 control/49 MWA/52 MwoA).
MWA, migraine with aura; MwoA, migraine without aura; IQR, interquartile range.