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B. breve R/M systems and corresponding methylation motifs. Locus maps showing the gene organization of each R/M system detected in B. breve. For each system the RM-COG number, assigned nomenclature, type of system (I, II or IIG) and type of modification (m6A, m5C or m4C) are indicated. Methylated motifs obtained by PacBio and BS-seq are also reported (blue for m6A, pink for m5C and yellow for m4C), with an indication of single-strand (*) and double strand (**) methylation.
