Table 1.
Study cohorts
| Characteristic | Cohort | ||
|---|---|---|---|
| CAPRISA | FHI‐360 | HPTN 039 | |
| Country of origin | South Africa | Zimbabwea | Zambia |
| Number of samples | 518 | 1839 | 85 |
| Number of unique subjects | 90 | 162 | 25 |
| Range of duration of infection in years | 0.06 to 3.7 | 0.04 to 9.9 | 0.15 to 0.8 |
| Mean samples per subject (range) | 6 (1 to 7) | 12 (1 to 20) | 4 (1 to 4) |
| Female sex, % of subjects | 100% | 100% | 100% |
| Number samples from subjects on ART (%) | 12 (2.2%) | 220 (11.3%) | 0 (0%) |
| Duration of infection in years | |||
| 0.0 to 0.5 | 159 | 306 | 42 |
| 0.5 to 1.0 | 173 | 262 | 43 |
| 1.0 to 2.0 | 88 | 448 | 0 |
| 2.0 to 3.0 | 76 | 105 | 0 |
| 3.0 to 5.0 | 22 | 347 | 0 |
| ≥ 5.0 | 0 | 371 | 0 |
| CD4 cell count | |||
| >500 | 228 | 685 | 54 |
| 500 to 200 | 271 | 822 | 26 |
| <200 | 14 | 104 | 0 |
| missing | 5 | 228 | 5 |
| Viral load (copies/mL) | |||
| >10,000 | 260 | 560 | 37 |
| 10,000 to 1000 | 161 | 278 | 26 |
| <1000 | 92 | 227 | 19 |
| missing | 5 | 774 | 3 |
a
All participants from South Africa, Zimbabwe and Zambia were assumed to have subtype C infection based on the prevalence of subtype C in those countries. The FHI‐360 cohort included one individual from Uganda with three samples. That individual was infected with HIV subtype C based on subtype assessment of the pol region.