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. 2018 Jan 13;46(4):2121–2132. doi: 10.1093/nar/gkx1319

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Specificity of molecular recognition of the CFX riboswitch and their impact on riboswitching. Left: Chemical structure of ciprofloxacin and seven selected fluoroquinolones that show binding to the CFX riboswitch. Chemical changes relative to CFX are shaded in light grey. Middle: Plot of log₁₀K_D values of the different fluoroquinolones and their activity in vivo (right), respectively (SD in brackets). Data shown in this graphical overview are summarized in Supplementary Table S9.