Table 4.
Data extracted from comparable studies in cognitive training studies
| Cognitive training Cognition scores |
P value | ||||||||
| Study | Number of subjects | Outcome scale | Control | Intervention | |||||
| Mean baseline score (SD) | Mean follow-up score (SD) | Change in mean score | Mean baseline score (SD) | Mean follow-up score (SD) | Change in mean score | ||||
| Tanaka et al24 | 34 | MMSE | – | – | – | 94.0 (5) | 99.0 (2.3) | 5 | <0.01* |
| Valentí Soler et al25 Phase 1 | 101 | MMSE | 12.1 (18.1) | 10.4 (15.7) | −1.7 | 11.8 (17.3) | 8.1 (15.0) | −3.7 | 0.022† |
| Valentí Soler et al25 Phase 2 | 110 | MMSE | 12.1 (18.1) | 10.4 (15.7) | −1.7 | 10.7 (16.5) | 9.1 (15.7) | −1.6 | 0.282† |
| Kim et al26 | 71 | ADAS-Cog | – | – | – | 89.9 (5.1) | 92.6 (4.0) | 2.7 | <0.001* |
*Study compares mean baseline score in intervention group to mean follow-up score in the intervention group.
†Study compares change in mean score from baseline to follow-up in control group to change in mean score from baseline to follow-up in intervention group.
ADAS-Cog, Alzheimer’s Disease Assessment Scale – cognitive subscale; MMSE, Mini-Mental State Examination.