Table 2.
Severity score (0 best and 100 worst) (n=14 990) |
Condition-specific quality of life (0 worst and 100 best) (n=14 586) |
Generic quality of life (0 death and 1 perfect health) (n=13 802) |
Symptoms ≥1 year (n=14 866) |
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Mean score (SE) |
Adjusted* difference (95% CI) |
P value | Mean score (SE) |
Adjusted* difference (95% CI) |
P value | Mean score (SE) | Adjusted* difference (95% CI) | P value | % (SE) | Adjusted* OR (95% CI) |
P value | |
Total | 61.8 (0.17) | 34.7 (0.18) | 0.65 (0.28) | 74.0 (0.36) | ||||||||
Age group | ||||||||||||
18–34 | 63.1 (0.44) | – | 33.2 (0.48) | – | 0.61 (0.007) | – | 70.7 (0.98) | – | ||||
35–39 | 62.9 (0.49) | −1.59 (−2.89 to 0.29) |
33.3 (0.51) | 1.75 (0.39 to 3.10) |
0.63 (0.008) | 0.03 (0.01 to 0.05) |
74.8 (1.00) | 1.25 (1.09 to 1.44) |
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40–44 | 62.5 (0.33) | −2.17 (−3.30 to 1.04) |
P<0.001 | 33.7 (0.35) | 2.59 (1.40 to 3.77) |
P<0.001 | 0.64 (0.005) | 0.04 (0.02 to 0.06) |
P<0.001 | 76.8 (0.67) | 1.39 (1.23 to 1.58) |
P<0.001 |
45–49 | 61.3 (0.31) | −3.36 (−4.47 to 2.51) |
35.4 (0.33) | 4.23 (3.06 to 5.39) |
0.67 (0.005) | 0.07 (0.05 to 0.08) |
74.2 (0.64) | 1.20 (1.06 to 1.35) |
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≥50 | 59.0 (0.47) | −5.88 (−7.19 to 4.58) | 38.2 (0.51) | 7.31 (5.93 to 8.68) |
0.70 (0.007) | 0.10 (0.07 to 0.12) |
70.9 (0.98) | 1.01 (0.88 to 1.16) |
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Ethnicity | ||||||||||||
White | 61.9 (0.19) | – | 34.8 (0.20) | – | 0.66 (0.003) | – | 74.1 (0.38) | – | ||||
Black or black British | 61.5 (0.82) | −1.93 (−3.51 to 0.35) |
35.0 (0.86) | 1.45 (−0.16 to 3.06) |
0.62 (0.01) | −0.01 (−0.08 to 0.02) |
79.4 (1.47) | 1.34 (1.11 to 1.62) |
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Asian or Asian British | 60.7 (1.02) | −2.38 (−4.25 to 0.51) |
P=0.011 | 34.2 (1.07) | 1.32 (−0.59 to 3.22) |
0.1392 | 0.58 (0.02) | −0.05 (−0.88 to 0.01) |
P<0.001 | 66.1 (1.49) | 0.70 (0.58 to 0.85) |
P<0.001 |
Other | 61.5 (1.33) | −0.46 (−3.09 to 2.16) |
33.9 (1.41) | −1.01 (−3.54 to 1.51) |
0.60 (0.02) | −0.05 (−0.30 to 0.20) |
72.3 (2.67) | 0.92 (0.70 to 1.20) |
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Socioeconomic deprivation (IMD) | ||||||||||||
Quintile 1 (most deprived) | 65.5 (0.37) | – | 30.5 (0.39) | – | 0.55 (0.007) | – | 72.0 (0.78) | – | ||||
Quintile 2 | 63.5 (0.38) | −1.53 (−2.57 to 0.50) |
33.1 (0.40) | 1.82 (0.75 to 2.90) |
0.62 (0.006) | 0.06 (0.05 to 0.08) |
73.6 (0.80) | 1.11 (0.99 to 1.24) |
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Quintile 3 | 61.6 (0.39) | −4.22 (−4.30 to 2.12) |
P<0.001 | 35.0 (0.41) | 3.44 (2.34 to 4.54) |
P<0.001 | 0.67 (0.006) | 0.09 (0.08 to 0.11) |
P<0.001 | 75.1 (0.81) | 1.20 (1.06 to 1.34) |
P=0.0091 |
Quintile 4 | 59.5 (0.41) | −6.02 (−6.02 to 3.87) |
36.8 (0.43) | 4.78 (3.66 to 5.90) |
0.71 (0.006) | 0.13 (0.12 to 0.15) |
74.5 (0.85) | 1.16 (1.03 to 1.31) |
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Quintile 5 (least deprived) | 58.2 (0.44) | −6.07 (−7.23 to 4.91) |
38.6 (0.46) | 6.29 (5.10 to 7.48) |
0.73 (0.006) | 0.14 (0.13 to 0.16) |
75.1 (0.91) | 1.21 (1.07 to 1.37) |
*All multivariable models were adjusted for body mass index, parity and number of comorbidities.
P values based on Wald test.
IMD, Index of Multiple Deprivation.