(b) Biomarker expression in phases I (prior to surgery) and II (after treatment) and its correlation with the stage of disease was compared in patients and P value was calculated

Biomarker expression	Phase I					Phase II
	Stage I		Stages II/III		P value	Stage I		Stages II/III		P value
	N	%	N	%		N	%	N	%
CK19	11	39	17	61	NS	5	29	12	71	NS
hMAM	10	59	7	41	0.004	9	53	8	47	0.034
HER2	0	0	0	0	—	0	0	0	0	—
MUC1	11	37	19	63	—	11	37	19	63	—
Myc	10	67	5	33	0.001	2	50	2	50	—
Ki-67	11	44	14	56	NS	8	60	5	40	0.013
ErbB2	10	67	5	33	0.001	0	0	15	100	≤0.001
ER	10	50	10	50	—	10	57	7	42.9	0.004
CEA	8	53	7	47	0.058	8	57	6	42.9	0.029

N: number of positive subjects; %: positivity percentage; P value ≤ 0.05 was considered statistically significant; NS: not significant.