. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: J Pediatr. 2017 Dec 18;194:87–93.e1. doi: 10.1016/j.jpeds.2017.11.012

Table IV. Multivariable analysis on the risk for PNAC.

	ITT (n = 223)			Per protocol (n = 206)
Parameter	aOR	95% CI	P	aOR	95% CI	P
SMOF-LE	0.428	0.155-1.187	.10	0.457	0.155-1.347	.16
NEC/FIP/GI surgery	5.481	1.894-15.868	.002	5.016	1.528-16.464	.008
Time on PN (d)	1.051	1.023-1.080	<.001	1.059	1.027-1.092	<.001
Feeding first wk (mL per feed/kg)	0.739	0.487-1.112	.16	0.665	0.413-1.073	.10

FIP, focal intestinal perforation; GI, gastrointestinal.

Analysis by ITT and per protocol. Binary logistic regression analysis showing the odds for the effect of SMOF-LE on PNAC compared with S-LE, adjusted for “compound outcome of NEC, FIP, and GI surgery,” time on parenteral nutrition and the median volume per enteral feed per kg birth weight in the first week of life. P values < .05 were considered statistically significant.