TABLE 1.
Comparison of patient and treatment characteristics in fresh versus frozen embryo transfer cycles.
| Fresh (n = 218) | Frozen (n = 122) | P valuea | |
|---|---|---|---|
| Source cycle | |||
| Infertility diagnosis | .680b | ||
| Tubal | 46 (21.1) | 25 (20.5) | |
| Male factor | 33 (15.1) | 24 (19.7) | |
| Anovulation | 39 (17.9) | 25 (20.5) | |
| Unexplained | 67 (30.7) | 37 (30.3) | |
| Endometriosis | 27 (12.4) | 11 (9.1) | |
| Otherc | 4 (1.8) | 0 (0) | |
| Unknown | 2 (0.9) | 0 (0) | |
| Fertilization rate | 67.21 ± .14 | 68.04 ± .16 | .621 |
| ICSI | 36 (16.5) | 16 (13.1) | .404 |
| OHSS | 49 (22.5) | 26 (21.3) | .804 |
| Embryo transfer cycle | |||
| Parity | 46 (21.1%) | 47 (38.5%) | <.001 |
| Age | 33.53 ± 3.59 | 33.71 ± 3.70 | .663 |
| Maximum E2 before embryo transfer | 4921.8 ± 1503.6 | 335.3 ± 141.8 | <.0001 |
| EMS thickness at transfer | 11.21 ± 2.30 | 10.31 ± 2.21 | .0006 |
| No. of embryos transfered | 2.68 ± 0.78 | 2.90 ± 0.97 | .022 |
| Implantation rate | |||
| Pregnancy plurality | .002 | ||
| Singleton | 122 (56.0) OR 0.39 |
93 (76.2) 95% CI 0.23–0.67 |
.0002 |
| Twin | 65 (29.8) OR 2.63 |
17 (13.9) 95% CI 1.43–5.00 |
.001 |
| Triplet | 6 (2.7) OR 1.69 |
2 (1.6) 95% CI 0.3–20.00 |
.52 |
Note: Continuous variables presented as mean ± SD, other values as n (%). CI = confidence interval; EMS = endometrial stripe; ICSI = intracytoplasmic sperm injection; OHSS = ovarian hyperstimulation syndrome; OR = odds ratio.
a
Generalized estimating equation adjustment for correlations.
b
Calculated after exclusion of other (n = 4) and unknown (n = 2), owing to small number of observations precluding use of chi-squared.
c
Other (n = 4): two with recurrent pregnancy loss, two with uterine abnormalities (bicornuate, fibroid).