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. Author manuscript; available in PMC: 2018 Feb 28.
Published in final edited form as: Sci Signal. 2017 Jan 31;10(464):eaaf7478. doi: 10.1126/scisignal.aaf7478

Fig. 7. AICAR regulates nucleosome remodeling and gene expression through AMPKα2 in vivo.

Fig. 7

Aortas were isolated from AMPKα2+/+ and AMPKα2−/− mice administered AICAR or metformin. (A) DNMT1 binding to promoters. (B) HAT1 binding to promoters. (C) Euchromatin abundance. (D) Methylation status. (E) Abundance of the indicated mRNAs. (F) Complex IV activity. n = 12 mice per genotype and treatment. *P < 0.05.