Table 2.
Day 56 Chimerism and Transplant outcomes and 95% CI-Significant differences highlighted
| D56 UCB CD33 Low (n=10) |
D56 UCB CD33 Moderate/full (n=29) |
P value | D56 UCB CD3 Mixed (n=16) |
D56 UCB CD3 Full (n=20) |
P value | D56 haplo CD3 Mixed (n=10) |
D56 haplo CD3 None (n=26) |
P value | D56 host CD3 Mixed (n=11) |
D56 host CD3 None (n=25) |
P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CI Relapse @ 1 year | 54% | 11% | 0.0001 | 46% | 12% | 0.007 | 40% | 15% | 0.009 | 33% | 16% | 0.09 |
| CI TRM@ 1 Year | 34% | 12% | 0.23 | 18 | 36 | 0.24 | 20% | 34% | 0.37 | 17% | 37% | 0.16 |
| KM PFS @ 1 year | 20% | 55% | 0.004 | 30% | 55% | 0.21 | 33% | 52% | 0.10 | 46% | 48% | 0.78 |
| KM OS@ 1 year | 30% | 62% | 0.02 | 50% | 48% | 0.92 | 44% | 55% | 0.48 | 61% | 48% | 0.30 |
| CI AGVHD gr II-IV@ d100 | 50% | 41% | 0.88 | 27% | 64% | 0.09 | 50% | 53% | 0.8 | 33% | 62% | 0.08 |
| CI cGVHD | 0% | 7% | 0.33 | 0% | 8% | 0.35 | 0% | 8% | 0.38 | 0% | 8% | 0.31 |