. 2017 Dec 7;64(1):65–74. doi: 10.1262/jrd.2017-127

Table 1. Transient inhibition of proteasome activity after fertilization affects full-term development.

MG132	No. of embryos used	Morphological stage of embryos at 24 hpi	No. of embryos transferred	No. (%) of
MG132	No. of embryos used	Morphological stage of embryos at 24 hpi	No. of embryos transferred	Implantations *	Fetuses **	Embryonically lethal ***
Treated without MG132 (Control)	154	2-cell	154	114 (74) ^a	108 (70) ^a	6 (5) ^a

Treated with MG132 for 8 h (from 1 to 9 hpi)	309	1-cell	221	119 (54) ^b	97 (44) ^b	22 (18) ^a
Treated with MG132 for 8 h (from 1 to 9 hpi)	309	2-cell	88	67 (76) ^{a, b}	46 (52) ^{a, b}	21 (31) ^a

*The percentage of transferred embryos that resulted in implantations. ** The percentage of transferred embryos that resulted in a live birth. *** The percentage of implanted embryos that resulted in embryonically lethal. Superscripts indicate significant differences from the control (P < 0.05).