Table 2. Development of mouse embryos treated with 5 µM MG132 for 6 h.
Duration of MG132 treatment (5 µM) | No. of embryos used | No. (%) of embryos developed to |
||||
3 or 4-cell embryos | 5–8-cell embryos | Morulae | Blastocysts | Degenerated | ||
Untreated | 54 | 54 (100) | 54 (100) | 54 (100) | 52 (96) | 2 (4) |
0–6 h (16.5–22.5 hpi) | 61 | 60 (98) | 60 (98) | 59 (97) | 57 (93) | 6 (10) |
6–12 h (22.5–28.5 hpi) | 61 | 60 (98) | 60 (98) | 60 (98) | 60 (98) | 2 (3) |
12–18 h (28.5–34.5 hpi) | 63 | 63 (100) | 62 (98) | 60 (95) | 56 (89) | 9 (14) |