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. 2018 Feb 28;9:867. doi: 10.1038/s41467-018-03058-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — DNA methylation at the VTRNA2-1 promoter. a Genomic locations of 6 HM450K probes associated with VTRNA2-1 promoter region. b DNA methylation levels (β-values) of these 6 probes labelled by breast cancer status. β-values for each individual are shown on y axis for 6 VTRNA2-1 probes. c Average DNA methylation levels across all six probes shown separately for individual families and labelled by breast cancer status. β-values are shown on y axis for members from each family (y axis)