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. 2018 Feb 28;8:3822. doi: 10.1038/s41598-018-22144-9

Table 3.

Significant clusters showing differential BOLD responses with respect to the GRAMMATICALITY and LEVEL OF EMBEDDING (LoE) of nested musical sequences.

Anatomical region BA Cluster size (voxels) MNI-coordinates t-value
X Y Z
UNGRAMMATICAL > GRAMMATICAL
R anterior insular cortex (AIC) 663 33 23 −2 8.42
R pars opercularis 44 51 17 10 8.05
R pars triangularis 45 48 23 26 7.12
R pars orbitalis 47 45 32 −6 7.46
R middle frontal gyrus 8 45 14 50 7.01
L/R Pre-supplementary motor area (pre-SMA) 8 234 6 32 46 8.78
−3 23 54 7.18
L anterior insular cortex (AIC) 72 −30 20 −6 7.89
R middle temporal gyrus 21 24 57 −43 −2 5.62
21/22 7 54 −25 −6 5.41
R dorsal premotor cortex 6 9 21 14 50 5.40
GRAMMATICAL > UNGRAMMATICAL
L/R ventromedial prefrontal cortex (vmPFC) 11 80 −12 41 −10 7.22
6 41 −14 6.27
TWO-LoE > ONE-LoE
R middle frontal gyrus 9 42 42 29 42 6.79
L inferior parietal lobule (IPL) 39/40 31 −54 −49 42 6.31
R inferior parietal lobule (IPL) 39 23 60 −49 30 6.26
Pre-supplementary motor area (pre-SMA) 8 21 −6 32 34 5.85
R dorsal premotor cortex 6 10 18 20 58 5.73
L middle frontal gyrus 9 8 −36 23 38 5.23
6/8 6 −39 14 54 5.33
L frontal pole 10 5 −33 53 −2 5.32
ONE-LoE > TWO-LoE
L supplementary motor area (SMA) 6/4 151 −36 −19 58 6.90
L premotor cortex 6 27 −6 2 54 6.03
L superior temporal gyrus 41 15 −54 −19 6 5.59
R superior temporal gyrus 22 14 66 −22 2 6.45

Notes: Reported clusters have a minimum cluster size of 4 voxels and were corrected for multiple comparisons voxel-wise using a threshold of p < 0.05. L – left hemisphere; R – right hemisphere; t-contrasts compared are shown in bold; Anatomical regions within each cluster are at least 4 mm apart and are ranked according to decreasing t-values.