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| First author | Phase | Schedule | Patients | RR (%) | mTTP/mPFS (months) | mOS (months) |
|---|---|---|---|---|---|---|
| Calabrò L (51) | II | Tremelimumab | 29 | 3.0 | 6.2 | 11.3 |
| Hassan R (52) | Ib | Avelumab | 53 | 9.0 | 4.0 | − |
| Maio M (53) | IIb | Tremelimumab | 382 | 4.5 | 2.8 | 7.7 |
| Placebo | 189 | 1.1 | 2.7 | 7.3 | ||
| Alley EW (54) | Ib | Pembrolizumab | 25 | 20.0 | − | − |
| Quispel-Janssen J (55) | II | Nivolumab | 38 | 13.2 | − | − |
RR, response rate; mTTP, median time to progression; mPFS, median progression free survival; mOS, median overall survival.
