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. 2017 Nov 21;118(4):546–557. doi: 10.1038/bjc.2017.411

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Copyright © 2018 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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Cadherin expression in BxPC-3 cell models and in primary cultures from human tumours. (A) Cadherin-1 or cadherin-3 expression was invalidated in BxPC-3 human pancreatic cancer cell line. Generated stable cell lines were called BxPC-3-cadh-1⁺ /cadh-3⁺ (no cadherin depletion), BxPC-3-cadh-1⁺ (cadherin-3 depletion) and BxPC-3-cadh-3⁺ (cadherin-1 depletion). Cadherin-1 and cadherin-3 expression was assessed by immunofluorescence. Scale bar: 15 μm. (B) Cadherin-1 and cadherin-3 were sequentially immunostained in CRCM110 and CRCM08 primary cell cultures derived from human tumours. Scale bar: 15 μm.