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. 2017 Nov 21;118(4):546–557. doi: 10.1038/bjc.2017.411

Figure 7.

Figure 7

Cadherins alter ECM deposition. Mice were orthotopically implanted with either BxPC-3-cadh-1+/cadh-3+, BxPC-3-cadh1+ or BxPC-3-cadh-3+ cells resuspended in Matrigel or with Matrigel alone (n=3 for each condition). (A) Mice were sacrificed 21 days after injection, pancreas were collected and the weight was measured. (B) Sections of graft tissue specimens were subjected to Masson’s trichrome staining. (C) The stromal area of each tumour was measured by microscopy (10 × objective) and analysed by ImageJ. ***P<0.001.