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. 2018 Feb 6;12(3):373–390. doi: 10.1002/1878-0261.12171

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© 2018 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Common transcription factors defined by two assays. (A) A comparison of the results of the transcription factor activation profiling plate with those of the online prediction database revealed common transcription factors. (B) CREB‐1 is predicted to bind after the 19‐bp polymorphism region. AP4 is predicted to bind within the 19‐bp polymorphism region. The LAPTM4B*1 promoter has only one TFAP4 binding site, whereas the LAPTM4B*2 promoter has two TFAP4 binding sites in the 19‐bp polymorphism region.