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. 2018 Feb 28;8:3773. doi: 10.1038/s41598-018-21885-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cell viability upon short-term CCT020312 treatment is not differentially affected between wt and 2b5^ho astrocytes. Cell viability was measured after 4 h of CCT020312 (CTT) treatment. Values are relative cell viability compared to vehicle-treated cultures. Graphs show average + SD (n = 3, wt CCT n = 2). P-values are shown in supplementary Table 1. Although cell viability was significantly reduced, no significant difference in response was observed between wt and 2b5^ho astrocyte cultures.