Table 3.
Anthropometric and cardiometabolic measures according to SDC3 polymorphism (rs2282440) genotypes.
| C/C | C/T | T/T | p | |
|---|---|---|---|---|
| n = 119 | n = 294 | n = 132 | ||
| Age, yrs | 39.2 | 37.2 | 38 | 0.2834 |
| Sex (women), % | 65.6 | 64.3 | 57.6 | 0.3324 |
| BMI, kg/m2 | 26.0 | 26.4 | 27.9 | 0.0132 |
| WC, cm | 82.8 | 83.5 | 87.4 | 0.039 |
| PFM, % | 31.9 | 32.3 | 34.0 | 0.0139 |
| SBP, mmHg | 122.5 | 123.9 | 127.2 | 0.14 |
| DBP, mmHg | 77.1 | 77.8 | 79.7 | 0.3282 |
| TG, mg/dl | 105.7 | 110.9 | 131.1 | 0.0407 |
| HDL-C, mg/dl | 57.4 | 56.1 | 52.2 | 0.0539 |
| FPG, mg/dl | 96.9 | 93.8 | 98.4 | 0.1857 |
| HOMA-IR | 2.6 | 2.9 | 3.3 | 0.2287 |
| HOMA-IR group | ||||
| ≥ 75%tile, n (%) | 39 (32.8) | 80 (27.2) | 53 (40.2) | 0.0437 |
| hs-CRP | 0.21 | 0.21 | 0.21 | 0.1374 |
| hs-CRP group | ||||
| ≥ 75%tile, n (%) | 27 (22.7) | 77 (26.2) | 49 (37.1) | 0.0205 |
| Obesity, n (%) | 68 (57.1) | 162 (55.1) | 96 (72.7) | 0.0058 |
p values were calculated by using the Proc CATMOD test for categorical variables after adjustment for sex and general linear models for continuous variables after adjustment for sex and age. BMI: body mass index; WC: waist circumference; PFM: percent fat mass; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; FPG: fasting plasma glucose; HOMA-IR indicates homeostasis model assessment for insulin resistance; hs-CRP: high-sensitivity C-reactive protein.