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. 2018 Feb 28;13(2):e0193559. doi: 10.1371/journal.pone.0193559

Table 4. Factors associated with general obesity in different models (A-OR = Adjusted Odd Ratios).

Model 1 Model 2 Model 3 Model 4 Model 5
OR 95% CI OR 95% CI OR 95% CI OR 95% CI OR 95% CI
Non-CKD Reference Reference Reference Reference Reference
CKD Stage 1 1.29 (0.80 to 2.07) 1.24 (0.73 to 2.09) 1.48 (0.85 to 2.61) 1.02 (0.55 to 1.90) 0.70 (0.34to 1.43)
CKD Stage 2 2.47 (1.79 to 3.40) 2.14 (1.53 to 2.99) 2.12 (1.50 to 3.00) 1.63 (1.14 to 2.34) 0.99 (0.66 to 1.47)
CKD Stage 3a 1.64 (1.43 to 1.90) 1.48 (1.28 to 1.71) 1.45 (1.24 to 1.69) 1.21 (1.02 to 1.42) 1.30 (1.09 to 1.55)
CKD Stage 3b 1.77 (1.28 to 2.45) 1.66 (1.17 to 2.36) 1.76 (1.21 to 2.55) 1.60 (1.07 to 2.38) 1.91 (1.24 to 2.94)
CKD Stage 4/5 1.29 (0.71 to 2.35) 1.32 (0.69 to 2.52) 1.57 (0.79 to 3.14) 1.01 (0.47 to 2.15) 1.05 (0.43 to 2.55)
Age, per 10-y older 1.04 (1.01 to 1.06) 1.02 (0.99 to 1.04) 0.89 (0.87 to 0.92) 0.84 (0.81 to 0.87)
Male, sex 1.50 (1.42 to 1.59) 1.48 (1.38 to 1.60) 1.33 (1.23 to 1.43) 0.68 (0.62 to 0.76)
Elementary to middle school 1.26 (1.17 to 1.36) 1.21 (1.12 to 1.32) 1.16 (1.06 to 1.26) 1.13 (1.03 to 1.24)
Residential area, rural 1.05 (0.97 to 1.13) 1.04 (0.95 to 1.13) 1.07 (0.98 to 1.16) 1.07 (0.98 to 1.17)
Living without spouse 0.81 (0.75 to 0.87) 0.79 (0.73 to 0.85) 0.74 (0.69 to 0.80) 0.82 (0.76 to 0.89)
Currently Unemployed 0.86 (0.81 to 0.92) 0.82 (0.77 to 0.88) 0.81 (0.76 to 0.87) 0.84 (0.78 to 0.91)
Health-related Factors
 Sleep Duration (hr.) 0.97 (0.94 to 0.99) 0.96 (0.94 to 0.99) 0.95 (0.93 to 0.97)
 Current smoking 1.00 (0.92 to 1.08) 1.02 (0.94 to 1.10) 0.88 (0.81 to 0.96)
 Alcohol drinking 0.98 (0.92 to 1.05) 0.92 (0.86 to 0.98) 1.05 (0.98 to 1.13)
 Perceived health status
  Very good/Good Reference Reference Reference
  Fair 1.13 (1.06 to 1.20) 1.07 (1.00 to 1.14) 1.00 (0.93 to1.08)
  Poor/Very poor 1.19 (1.08 to 1.31) 1.04 (0.94 to 1.15) 1.01 (0.91 to 1.12)
 EQ-5D 0.45 (0.33 to 0.60) 0.40 (0.30 to 0.55) 0.40 (0.29 to 0.55)
 Depressive Symptom (Yes) 0.92 (0.84 to 1.02) 0.94 (0.85 to 1.04) 0.94 (0.84 to 1.05)
 Perceived psychological stress 1.15 (1.07 to 1.24) 1.13 (1.05 to 1.22) 1.11 (1.02 to 1.20)
 Suicidal ideation 0.90 (0.82 to 0.99) 0.90 (0.81 to 0.99) 0.89 (0.80 to 0.99)
Comorbidity
 Cancer 0.85 (0.70 to 1.03) 0.90 (0.74 to 1.10)
 Ischemic heart disease 1.00 (0.81 to 1.24) 1.34 (1.08 to 1.65)
 Stroke 0.94 (0.76 to 1.17) 1.11 (0.89 to 1.39)
 Hypertension 2.59 (2.40 to 2.79) 1.66 (1.51 to 1.83)
 Diabetes mellitus 1.61 (1.46 to 1.78) 1.08 (0.93 to 1.25)
 Anemia 0.63 (0.56 to 0.71) 1.15 (1.00 to 1.34)
 COPD or Asthma 0.98 (0.82 to 1.17) 1.09 (0.90 to 1.32)
Examination/Lab Tests
 SBP, per 10 mmHg 1.05 (1.02 to 1.09)
 DBP, per 10 mmHg 1.27 (1.21 to 1.34)
 Total cholesterol, per 10 mg/dL 1.10 (1.08 to 1.11)
 HDL-C, per 10 mg/dL 0.63 (0.61 to 0.65)
 Triglycerides, per 10 mg/dL 1.00 (1.00 to 1.01)
 Hemoglobin per 1g/dL 1.17 (1.13 to 1.22)
 Fasting blood sugar, per 10 mg/dL 1.08 (1.06 to 1.11)

Note: 1) Model 1 was unadjusted; Model 2 was adjusted for the variables in Model 1 and sociodemographic factors (age, sex, education, residence, living with a spouse, and currently unemployed); Model 3 was adjusted for the variables in Model 2 and health-related characteristics (sleep duration, smoking, alcohol drinking, perceived health status, EQ-5D, depressive symptoms, perceived psychological stress, and suicidal ideation); Model 4 was adjusted for the variables in Model 3 and comorbidities (cancer, ischemic heart disease, stroke, hypertension, diabetes mellitus, anemia, and chronic obstructive pulmonary disease or asthma); Model 5 was adjusted for the variables in Model 4 and laboratory measurements (SBP, DBP, total cholesterol, high-density lipoprotein cholesterol, triglycerides, hemoglobin, and fasting blood sugar); 2) EuroQoL: visual analogue scale and level were examined only in 2010–2012; Fe levels were measured only in 2008–2012 and were therefore omitted from adjustments.