Table 1. Fold changes (log2) and adjusted P-values of PDCD1, CD274 (PD-L1) and PDCD1LG2 (PD-L2) in different group comparisons as indicated in each row.
The same synovial biopsies in each group as in Fig 1 was used in the analysis.
| mRNA | Group 1 | Group2 | Log2 Fold change | adjusted P value |
|---|---|---|---|---|
| PDCD1 | normal | OA | -0.85 | 7.97E-01 |
| PDCD1 | normal | Arthralgia | -1.05 | 4.17E-01 |
| PDCD1 | normal | UA | 0.49 | 7.90E-01 |
| PDCD1 | normal | Early RA | 2.52 | 4.38E-04 |
| PDCD1 | normal | Est RA | 1.49 | 2.63E-02 |
| PD-L1(CD274) | normal | OA | -0.21 | 8.68E-01 |
| PD-L1(CD274) | normal | Arthralgia | 2.09 | 9.50E-05 |
| PD-L1(CD274) | normal | UA | 2.63 | 1.02E-04 |
| PD-L1(CD274) | normal | Early RA | 2.46 | 1.07E-12 |
| PD-L1(CD274) | normal | Est RA | 2.39 | 9.09E-14 |
| PD-L2 (PDCD1LG2) | normal | OA | 0.36 | 6.47E-01 |
| PD-L2 (PDCD1LG2) | normal | Arthralgia | 2.02 | 9.74E-07 |
| PD-L2 (PDCD1LG2) | normal | UA | 2.39 | 4.86E-06 |
| PD-L2 (PDCD1LG2) | normal | Early RA | 2.08 | 7.67E-15 |
| PD-L2 (PDCD1LG2) | normal | Est RA | 1.94 | 3.90E-15 |