Skip to main content
. 2018 Feb 28;13(2):e0192947. doi: 10.1371/journal.pone.0192947

Fig 1. Overview of crossover study design (adapted from Burton et al., 2017 [21]).

Fig 1

A. Probiotic yoghurt and acidified milk were consumed during two test phases. Postprandial dairy tests (D1 and D2) were completed at the beginning of each test phase and fasting tests were completed after two weeks intake of each product (Fasting 1 and 2). Run-in and wash-out periods respectively preceded and followed the two test phases. Three-day controlled diets were provided prior to all test days and dairy intake was restricted during all study phases. B. Blood sampling on D1 and D2 assessed metabolic, inflammatory and gene expression changes in the six-hour period following dairy intake. All parameters were assessed for the fasting tests. Abbreviations: HOMA, homeostatic model assessment; NEFA, non-esterified fatty acids; hsCRP, high sensitivity C-reactive protein; LPS, lipopolysaccharide; CCL2, chemokine ligand 2; CCL5, chemokine ligand 5; IL6, interleukin 6; TNFα, tumor necrosis factor alpha.