Skip to main content
. 2018 Jan 30;2(3):329–343. doi: 10.1002/hep4.1145

Figure 4.

Figure 4

IL‐17 deficiency represses liver inflammation, including IL‐27 production. (A) mRNA expression of MCP1 and F4/80 were quantified by qRT‐PCR. (B) Liver macrophage infiltration was analyzed by F4/80 immunostaining and counting. (C) TNF‐α, IL‐6, and IL‐27 (Ebi3 and IL‐27p28 subunits) mRNA expressions were quantified by qRT‐PCR in WT and IL‐17−/− mice after 3, 10, or 21 days of the CDE diet. *P < 0.05, **P < 0.01, ***P < 0.005, WT versus IL‐17−/− mice. (D) Inflammatory gene expressions were quantified by qRT‐PCR in the IL‐17‐treated RAW264.7 macrophage cell line. Data represent mean ± SEM. Abbreviations: CT, control; d, day; qRT‐PCR, quantitative reverse‐transcription polymerase chain reaction.