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. Author manuscript; available in PMC: 2018 Aug 14.
Published in final edited form as: N Engl J Med. 2017 Feb 14;379(13):1234–1243. doi: 10.1056/NEJMoa1613108

Table 1.

Characteristics of the Participants at Baseline.

Characteristic Participants (N = 150)
Age
 Mean (range) — yr 37.8 (<1 to 83)
 Age group — no. (%)
  0–17 yr 17 (11.3)
  18–64 yr 124 (82.7)
  ≥65 yr 9 (6.0)
Female sex — no. (%) 66 (44.0)
Pregnancy — no. (%) 5 (3.3)
Presence of signs or symptoms of Zika virus infection at enrollment — no. (%)
 No* 4 (2.7)
 Yes 146 (97.3)
Days after symptom onset at enrollment — no./total no. (%)
 0–2 days 66/146 (45.2)
 3–5 days 63/146 (43.2)
 6–7 days 5/146 (3.4)
 8–14 days 4/146 (2.7)
 ≥15 days 8/146 (5.5)
Signs or symptoms at enrollment — no./total no. (%)
 Fever 115/146 (78.8)
 Red eyes or eye pain 119/146 (81.5)
 Rash 135/144 (93.8)
 Pruritus 117/145 (80.7)
 Photophobia 59/144 (41.0)
 Edema 92/145 (63.4)
 Arthralgia 120/139 (86.3)
 Myalgia 102/125 (81.6)
 Headache 115/145 (79.3)
 Abdominal pain 73/145 (50.3)
 Lymphadenopathy 50/144 (34.7)
 Diarrhea 62/145 (42.8)
 Nausea 63/145 (43.4)
 Vomiting 17/145 (11.7)
 Pelvic pain 25/139 (18.0)
 Dysuria 25/145 (17.2)
 Other 129/144 (89.6)
Laboratory findings
 Median white-cell count (range) per mm3 5200 (2100 to 40,000)
 Median platelet count (range) per mm3 216,000 (80,000 to 373,000)
 Median hematocrit (range) — % 42.2 (30.9 to 51.9)
*

This category includes two participants who were asymptomatic at baseline but in whom signs or symptoms developed within 7 days after specimen collection.

The median duration of fever was 2 days (range, 1 to 22); red eyes, 3 days (range, 1 to 7); and rash, 5 days (range, 1 to 25).

Other signs or symptoms included cough (in 33.1% of the participants), yellow eyes or skin (4.8%), difficulty urinating (7.8%), blood in urine (5.5%), painful ejaculation (6.7% of men), and penile discharge (2.7% of men).