Contemporary statin guidelines were applied to 1,475 young adults not on statins prior to myocardial infarction. (Left) The stepwise implementation of the 2013 American College of Cardiology/American Heart Association cholesterol guidelines. (Right) The stepwise implementation of the 2016 United States Preventive Services Task Force statin recommendations. The cohort is stratified by statin eligibility according to specified guideline criteria into 3 groups: statin recommended (green), statin considered (gray), and statin not recommended (orange). The risk factors considered by USPSTF guidelines include diabetes, hypertension, dyslipidemia, and smoking. ACC/AHA = American College of Cardiology/American Heart Association; ASCVD = atherosclerotic cardiovascular disease; CV = cardiovascular; LDL = low-density lipoprotein; MI = myocardial infarction; USPSTF = U.S. Preventive Services Task Force.