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. 2018 Mar 1;18:238. doi: 10.1186/s12885-018-4143-x

Fig. 7.

Fig. 7

The effects of trastuzumab on the phosphorylation of ERK and AKT in CHO-K6 cells. The phosphorylation of ERK and AKT was revealed by immunoblotting as described in Materials and Methods. a The phosphorylation of ERK and AKT in CHO parental cells and in CHO-K6 cells. b The effects of trastuzumab on the phosphorylation of ERK and AKT in CHO-K6 cells. Cells were treated with trastuzumab with indicated concentrations for 7 h. Cells treated with normal human IgG was used as negative control and cells treated with CP-714724 (CP) was used as positive control