. Author manuscript; available in PMC: 2018 Oct 1.

Published in final edited form as: Cancer Res. 2017 Aug 17;77(19):5327–5338. doi: 10.1158/0008-5472.CAN-17-1355

Table 1.

Spontaneous chromosomal anomalies in Mre11/Artemis deficient MEFS

Geneotype	Mre11^cond/−	Mre11^−/−	Mre11^cond/− Art^−/−	Mre11^−/−Art^−/−
Total Metaphases	140	141	166	151
Gaps/Breaks	18 (0.13)	195 (1.38)	34 (0.20)	67 (1.77)
Fragments	56 (0.40)	187 (1.33)	58 (0.35)	271 (1.79)
Ring	0 (0)	0 (0)	1 (0.01)	7 (0.05)
Dicentric	1 (0.01)	12 (0.09)	3 (0.02)	27 (0.18)
Radial	1 (0.01)	21 (0.15)	1 (0.01)	32 (0.21)
Robertsonian translocations	0 (0)	4 (0.03)	1 (0.01)	12 (0.08)

Total anomalies	76	419	98	616
Anomalies per metaphase	0.54	2.97	0.59	4.08