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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Trends Endocrinol Metab. 2018 Feb 3;29(3):140–150. doi: 10.1016/j.tem.2018.01.002

Figure 2. Hepatic bilirubin elimination.

Figure 2

Unconjugated bilirubin enters hepatocytes through the organic anion transporter (OATP) and is conjugated with glucuronic acid (GA) by UDP-glucuronyltransferase UGT1A1 and excreted by multi-drug resistant protein (MRP2) to bile. Soluble bilirubin is secreted back into the blood by MRP3.

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