Table 1.
Hypothesized relationship between QLQ-C30 and SCNS domains/items and resulting areas under the curve (AUC)
| EORTC Domain | SCNS Domain/Item(s) | AUC |
|---|---|---|
|
| ||
| Hypothesized Strong Relationship | ||
|
| ||
| Physical Function | Physical & Daily Living Needs Domaina (overall domain score and individual items) | .69–.81 |
|
| ||
| Role Function | Work around the home | .71–.73 |
| Not being able to do the things you used to | ||
|
| ||
| Emotional Function | Psychological Needs Domaina (overall domain score and individual items) | .56–.74 |
|
| ||
| Pain | Pain | .78 |
|
| ||
| Fatigue | Lack of energy/tiredness | .74 |
|
| ||
| Hypothesized Moderate Relationship | ||
|
| ||
| Social Function | Not being able to do the things you used to | .64 |
|
| ||
| Sleep | Lack of energy/tiredness | .41–.51 |
| Feeling unwell a lot of the time | ||
| Being given information…about aspects of managing your illness and side-effects at home | ||
|
| ||
| Hypothesized Weak Relationship | ||
|
| ||
| Cognitive Function | Not being able to do the things you used to | .54 |
|
| ||
| Global Health /QOL | Feeling unwell a lot of the time | .73 |
|
| ||
| Nausea/Vomiting | Feeling unwell a lot of the time | .19–.36 |
|
|
|
|
| Dyspnea | .37–.48 | |
|
|
|
|
| Appetite Loss | Being given information…about aspects of managing your illness and side-effects at home | .47–.49 |
|
|
|
|
| Constipation | .31–.37 | |
|
|
|
|
| Diarrhea | .34 | |
a
When SCNS domains were used, we examined both the overall domain score and the scores for the individual items that comprise the domain.