Table 1.

GFR and Cr Clearance Estimating Equations Validated in Patients with Cirrhosis

GFR and Cr Clearance Estimating Equations		Original GFR Equation Development Studies	Renal Marker Used	Population from which the GFR Equation was Derived	Most Recent External Validation Studies in Patients with Cirrhosis
Cr Equations	Cockcroft-Gault12	Cockcroft and Gault (1976)12	Cr	Patients from Queen Mary Veterans’ Hospital	Francoz (2010)26, Mindikoglu (2014)9
	MDRD-417-19	Levey (1999)17, Levey (2006)18, Levey (2007)19	Cr	CKD	Francoz (2010)26, Francoz (2014)25, De Souza (2014)24, Mindikoglu (2014)9, Cholongitas (2017)23, Kalafateli (2017)15
	MDRD-617-19	Levey (1999)17, Levey (2006)18, Levey (2007)19	Cr	CKD	Francoz (2014)25, De Souza (2014)24, Mindikoglu (2014)9, Kalafateli (2017)15
	CKD-EPI Cr 2020	Levey (2009)20	Cr	With and without CKD	Francoz (2010)26, Francoz (2014)25, De Souza (2014)24, Mindikoglu (2014)9, Cholongitas (2017)23, Kalafateli (2017)15
	Royal Free Hospital Cirrhosis GFR15	Kalafateli (2017)15	Cr	Cirrhosis	Kalafateli (2017)15
Cystatin C Equations	LARSSON16	Larsson (2004)16	Cystatin C	University Hospital MAS	Mindikoglu (2014)9, Cholongitas (2017)23
	HOEK13	Hoek (2003)13	Cystatin C	With suspected or established renal dysfunction	De Souza (2014)24, Mindikoglu (2014)9, Cholongitas (2017)23
	CKD-EPI Cystatin C (2012)14	Inker (2012)14	Cystatin C	With and without CKD	De Souza (2014)24, Mindikoglu (2014)9, Cholongitas (2017)23, Kalafateli (2017)15
Cr-Cystatin C Equations	STEVENS22	Stevens (2008)22	Combined Cr and cystatin C	CKD	Mindikoglu (2014)9
	CKD-EPI Cr-Cystatin C (2012)14	Inker (2012)14	Combined Cr and cystatin C	With and without CKD	De Souza (2014)24, Mindikoglu (2014)9, Cholongitas (2017)23, Kalafateli (2017)15
	Cr-Cystatin C GFR Equation for Cirrhosis21	Mindikoglu (2016)21	Combined Cr and cystatin C	Cirrhosis	Cholongitas (2017)23