Table 1. showing the baseline characteristics of adult patients with acute respiratory failure requiring more than 1 day of invasive mechanical ventilation.

Baseline Characteristics	Total N=1157	Not Frail N=541	Frail N=616	P value
Age, mean (SD)	67.1 (16.4)	62.9 (17.1)	70.8 (14.7)	<0.001
Male Gender, n (%)	520 (44.9)	243 (44.9)	277 (45.0)	0.986
Race, n (%)				0.091
White	292 (25.2)	135 (25.0)	157 (25.5)
Black/African American	376 (32.5)	160 (29.6)	216 (35.1)
Alaska/Pacific/Asian	29 (2.5)	14 (2.6)	15 (2.4)
Other/Unknown	460 (39.8)	232 (42.9)	228 (37.0)
Hispanic Ethnicity, n (%)	421 (36.4)	212 (39.2)	209 (33.9)	0.147
BMI, mean (SD)	28.4 (9.3)	29.1 (9.9)	27.8 (9.1)	0.034
Admitted from nursing home, n (%)	114 (9.9)	23 (4.3)	91 (14.8)	<0.001
SOFA Score, median (IQR)	8 (6-12)	9 (7-12)	8 (5-11)	<0.001
Charlson Co-Morbidity Score, median (IQR)	4 (2-6)	4 (2-6)	4 (2-6)	<0.001

Abbreviations: SD – Standard Deviation; SOFA – Sequential Organ Failure Assessment; IQR – Interquartile Range.