Skip to main content
. Author manuscript; available in PMC: 2019 Mar 2.
Published in final edited form as: J Mol Biol. 2018 Jan 10;430(5):695–709. doi: 10.1016/j.jmb.2018.01.002

Fig. 7.

Fig. 7

19F CODEX data of membrane-bound TMD. (a) L493F-TMD in the POPC/cholesterol membrane. Representative S0 and S spectra are shown. (b) L493F-TMD in the POPE membrane. (c) L504F-TMD in the POPC/cholesterol membrane. (d) L500F-TMD in the POPC/cholesterol membrane. The data were acquired at 230 K under 8 kHz MAS. The percentages of α-helix and β-strand are taken from Table S1, and intermolecular 19F–19F distances in the β-sheet are fixed to 4.8 Å in the simulation. The CODEX intensities of L493F and L504F equilibrate to 0.33, indicating that the TMD is trimerized. The L500F CODEX decay is slower, indicating longer interhelical distances.

HHS Vulnerability Disclosure