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. Author manuscript; available in PMC: 2019 Feb 28.
Published in final edited form as: J Am Chem Soc. 2018 Feb 13;140(8):3128–3133. doi: 10.1021/jacs.8b00172

Figure 5.

Figure 5

Chemical stability of the intramolecular crosslinked peptide 3 (100 μM) under (a) basic (500 μM K2CO3) condition; (b) acidic (10 mM HCl) condition; (c) oxidative conditions (air) in Tris buffer (100 mM, pH 7.5) and (d) in the presence of glutathione (500 μM) in Tris buffer (100 mM, pH 7.5). LC-MS analysis indicated that little or no decomposition had occurred after 24 hours.