Figure 13.

Electrostatic contributions to protein–protein binding stability and rate constants. (a) Electrostatic components, $\mathrm{\Delta }{G}_{\text{bind}}^{\text{el}}$, of the interaction energies in 132 protein–protein native complexes. (b) Electrostatic interaction energies, ΔG^el*, in the transient complexes of the 132 protein pairs. Reprinted with permission from ref 452. Copyright 2013 John Wiley & Sons Ltd.