Table 1.
Demographics and echocardiographic characteristics of the study populations
| HyperGEN (N= 1,934) | GENOA (N= 1,090) | P* | |
|---|---|---|---|
| Age, years | 46.3 ± 13.2 | 61.8 ± 10.1 | <0.0001 |
| Female, % | 63.1% | 71.3% | <0.0001 |
| Body mass index, kg/m2 | 32.0 ± 7.7 | 31.6 ± 6.6 | 0.13 |
| Centers in Alabama, % | 75.2% | 0% | <0.0001 |
| Hypertension, % | 65.7% | 82.3% | <0.0001 |
| Diabetes, % | 20.1% | 30.5% | <0.0001 |
| Left ventricular traits | |||
| Left ventricular mass, g | 170.2 ± 49.4 | 160.0 ± 44.6 | <0.0001 |
| Left ventricular internal dimension-diastole, cm | 5.2 ± 0.5 | 5.2 ± 0.5 | 0.99 |
| Relative wall thickness | 0.34 ± 0.06 | 0.32 ± 0.05 | 0.003 |
| Fractional shortening, % | 33.3 ± 5.5 | 32.9 ± 4.6 | 0.003 |
| The ratio of left ventricular transmitral early velocity to late/atrial velocity | 1.2 ± 0.5 | 1.1 ± 0.38 | <0.001 |
| Left atrial dimension, cm | 3.4 ± 0.5 | 3.6 ± 0.5 | <0.001 |
*
Numeric variables were presented as mean ± SD, categorical variables were presented as percentages. Significance determined using Chi-square test for categorical and two independent sample t-test for continuous.