Table 3.

Prospective Clinical Trials of Positive Airway Pressure Therapy in Surgical Patients With Undiagnosed OSA or Untreated OSA

Feature	Guralnick et al, 201269 (n = 211)	Liao et al, 201344 (n = 177)	O’Gorman et al, 201345 (n = 138)
Study type	Retrospective observational study	RCT	RCT
Study objective	CPAP adherence during perioperative period	Effect of APAP on AHI and oxygenation	Effect of APAP on hospital stay and postoperative Cx
Timing of APAP	CPAP started preoperatively, followed for adherence postoperatively	3 days preoperatively and 5 days postoperatively	APAP started in PACU and during night and whenever patient sleeps
Study outcome	Median CPAP adherence 2.5 h/night Optimal pressure 9 ± 2 cm H2O	APAP adherence 45% Preoperative AHI vs postoperative AHI (NS) APAP: 30.1 to 3.0 (P < .001) No-APAP: 30.4 to 31.9 (P = .302)	Any complications: 20.9 vs 23.3% (P = 1.0) LOS median, 5 vs 4 days; P = .02
Duration of APAP during first night after surgery	NA	4.1 ± 5.3 h	6.2 h (1.3-9.3 h)
PAP adherence (per night)	Median 2.5 h/night (0.7-4.5)	0-3.8 h/night, mean 2.4-4.6 h/night	3.0 h (1.0-7.5 h/night)

See Table 1 legend for expansion of abbreviations.