Table 1.
Demographic Characteristics and Metabolic Data in Children With and Without Endothelial Dysfunction
| Variables | NEF (n = 25) | Endothelial Dysfunction (n = 35) | P Value |
|---|---|---|---|
| Age, y | 7.59 ± 1.26 | 8.41 ± 1.20 | .14 |
| BMI z-score | 1.69 ± 0.62 | 2.00 ± 0.68 | .43 |
| Sex, % male | 70.4 | 63.8 | .35 |
| Ethnicity, % | |||
| White | 77.3 | 74.1 | .21 |
| African American | 22.4 | 26.2 | .26 |
| SBP, mm Hg | 107.55 ± 10.35 | 107.32 ± 10.68 | .47 |
| DBP, mm Hg | 62.28 ± 8.15 | 63.56 ± 7.16 | .32 |
| Tmax, s | 26.84 ± 11.35 | 62.42 ± 15.88 | .0001 |
| TG, mg/dL | 67.30 ± 30.71 | 89.0.06 ± 53.64 | .04 |
| TC, mg/dL | 160.34 ± 27.41 | 164.90 ± 26.98 | .27 |
| HDL-C, mg/dL | 52.78 ± 7.44 | 49.01 ± 7.60 | .03 |
| LDL-C, mg/dL | 94.04 ± 22.49 | 98.06 ± 23.87 | .27 |
| Glucose, mg/dL | 76.23 ± 9.90 | 81.45 ± 13.43 | .15 |
| Insulin, mg/dL | 5.88 ± 2.98 | 9.11 ± 6.53 | .02 |
| HOMA-IR | 0.98 ± 0.79 | 1.66 ± 1.58 | .04 |
| hsCRP, mg/dL | 0.43 ± 0.31 | 1.51 ± 1.18 | .007 |
Data presented as mean ± SD unless otherwise noted. DBP = diastolic BP; HDL-C = high-density lipoprotein cholesterol; HOMA-IR = homeostatic model assessment-insulin resistance; hsCRP = high-sensitivity C-reactive protein; LDL-C = low-density lipoprotein cholesterol; NEF = normal endothelial function; SBP = systolic BP; TC = total cholesterol; TG = triglyceride; Tmax = time of maximum perfusion after occlusion release.