DTI Measures in posterior limb (PLIC) and retrolenticular internal capsule (RLIC). (A) PLIC: The left (pink) and right (green) three-dimensional ROIs are shown in the left panel. The corresponding scatter plots show lower FA values in TBI patients (red dots) compared to controls (blue triangles) in both hemispheres. Two of the TBI patients showed lesions within the right PLIC (red dots with black outline), as shown in the upper right panel. (B) RLIC: The three-dimensional ROI (pink) is illustrated on an axial MRI. The scatter plots show higher RD and MD and lower FA in TBI patients compared to controls. Only 2 TBI subjects had lesions within this ROI (white arrow in MRI). See Table 2 and text for corrected p values. ANCOVA, analysis of covariance; DTI, diffusion-tensor imaging; FA, fractional anisotropy; MD, mean diffusivity; MRI, magnetic resonance imaging; RD, radial diffusivity; ROI, region of interest; TBI, traumatic brain injury.