Table 2.
Fractional Anisotropy (FA) and Diffusivity in Different Brain Regions (Mean ± SE) of TBI Subjects and Controls
| TBI subjects (n = 15) | Controls (n = 18) | |||||
|---|---|---|---|---|---|---|
| Brain region | Left | Right | Left | Right | TBI vs. controls ANCOVA-corr-p value (left) | TBI vs. controls ANCOVA-corr-p value (right) |
| Fractional anisotropy (FA) | ||||||
| Anterior corona radiata (ACR) | 0.315 ± 0.010 | 0.332 ± 0.008 | 0.345 ± 0.007 | 0.366 ± 0.006 | 0.99 | 0.99 |
| Superior corona radiata (SCR) | 0.345 ± 0.006 | 0.335 ± 0.007 | 0.364 ± 0.005 | 0.365 ± 0.005 | 0.99 | 0.10 |
| Posterior corona radiata (PCR) | 0.338 ± 0.006 | 0.324 ± 0.010 | 0.368 ± 0.005 | 0.360 ± 0.007 | 0.09 | 0.56 |
| Corticospinal tract | 0.347 ± 0.009 | 0.346 ± 0.009 | 0.363 ± 0.007 | 0.356 ± 0.009 | 0.99 | 0.99 |
| Superior longitudinal fasciculus (SLF) | 0.332 ± 0.007 | 0.318 ± 0.005 | 0.366 ± 0.004 | 0.347 ± 0.004 | 0.007 | 0.004 |
| Posterior limb internal capsule (PLIC) | 0.490 ± 0.007 | 0.472 ± 0.011 | 0.526 ± 0.005 | 0.527 ± 0.005 | 0.008 | 0.004 |
| Retrolenticular IC | 0.388 ± 0.006 | 0.396 ± 0.007 | 0.411 ± 0.005 | 0.433 ± 0.006 | 0.50 | 0.04 |
| Genu of corpus callosum (CC) | 0.480 ± 0.014 | 0.542 ± 0.009 | 0.02 | |||
| Body of CC | 0.400 ± 0.017 | 0.467 ± 0.010 | 0.08 | |||
| Splenium of CC | 0.481 ± 0.016 | 0.549 ± 0.006 | 0.015 | |||
| Radial diffusivity (RD) | ||||||
| Anterior corona radiata (ACR) | 6.93 ± 0.264 | 6.52 ± 0.096 | 6.26 ± 0.077 | 6.09 ± 0.072 | 0.99 | 0.07 |
| Superior corona radiata (SCR) | 6.02 ± 0.099 | 6.14 ± 0.105 | 5.72 ± 0.047 | 5.75 ± 0.056 | 0.63 | 0.14 |
| Posterior corona radiata (PCR) | 6.53 ± 0.085 | 6.92 ± 0.111 | 5.98 ± 0.069 | 6.29 ± 0.086 | 0.002 | 0.009 |
| Corticospinal tract | 6.47 ± 0.088 | 6.43 ± 0.117 | 6.65 ± 0.126 | 6.59 ± 0.145 | 0.99 | 0.99 |
| Superior longitudinal fasciculus (SLF) | 6.38 ± 0.096 | 6.51 ± 0.085 | 5.91 ± 0.053 | 6.07 ± 0.061 | 0.01 | 0.01 |
| Posterior limb internal capsule (PLIC) | 5.09 ± 0.078 | 5.41 ± 0.168 | 4.78 ± 0.057 | 4.85 ± 0.048 | 0.35 | 0.19 |
| Retrolenticular IC | 6.39 ± 0.077 | 6.77 ± 0.120 | 6.07 ± 0.062 | 6.06 ± 0.065 | 0.27 | 0.0006 |
| Genu of corpus callosum (CC) | 6.33 ± 0.163 | 5.67 ± 0.099 | 0.05 | |||
| Body of CC | 7.25 ± 0.228 | 6.79 ± 0.120 | 0.99 | |||
| Splenium of CC | 6.33 ± 0.147 | 5.63 ± 0.067 | 0.007 | |||
| Mean diffusivity (MD) | ||||||
| Anterior corona radiata (ACR) | 8.39 ± 0.250 | 8.00 ± 0.095 | 7.80 ± 0.058 | 7.71 ± 0.057 | 0.99 | 0.99 |
| Superior corona radiata (SCR) | 7.41 ± 0.106 | 7.50 ± 0.114 | 7.15 ± 0.044 | 7.21 ± 0.051 | 0.99 | 0.99 |
| Posterior corona radiata (PCR) | 8.03 ± 0.086 | 8.37 ± 0.111 | 7.55 ± 0.061 | 7.87 ± 0.067 | 0.007 | 0.02 |
| Corticospinal tract | 7.96 ± 0.085 | 7.91 ± 0.112 | 8.33 ± 0.125 | 8.20 ± 0.138 | 0.99 | 0.99 |
| Superior longitudinal fasciculus (SLF) | 7.77 ± 0.088 | 7.80 ± 0.081 | 7.38 ± 0.047 | 7.47 ± 0.050 | 0.04 | 0.13 |
| Posterior limb internal capsule (PLIC) | 7.28 ± 0.080 | 7.58 ± 0.149 | 7.14 ± 0.051 | 7.26 ± 0.044 | 0.99 | 0.99 |
| Retrolenticular IC | 8.15 ± 0.082 | 8.66 ± 0.144 | 7.93 ± 0.049 | 8.05 ± 0.052 | 0.99 | 0.02 |
| Caudate | 9.22 ± 0.133 | 9.29 ± 0.178 | 8.66 ± 0.105 | 8.91 ± 0.102 | 0.07 | 0.99 |
| Putamen | 7.85 ± 0.151 | 7.80 ± 0.174 | 7.49 ± 0.087 | 7.23 ± 0.078 | 0.99 | 0.35 |
| Globus pallidus | 8.40 ± 0.215 | 8.69 ± 0.293 | 8.07 ± 0.087 | 8.07 ± 0.100 | 0.99 | 0.99 |
| Thalamus | 8.83 ± 0.078 | 9.08 ± 0.076 | 8.41 ± 0.053 | 8.76 ± 0.052 | 0.007 | 0.12 |
| Genu of corpus callosum (CC) | 9.01 ± 0.130 | 8.72 ± 0.069 | 0.99 | |||
| Body of CC | 9.51 ± 0.196 | 9.50 ± 0.078 | 0.99 | |||
| Splenium of CC | 9.00 ± 0.141 | 8.72 ± 0.058 | 0.99 | |||
ANCOVA, analysis of covariance; TBI, traumatic brain injury.