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. 2018 Mar 1;18:101. doi: 10.1186/s12879-018-2993-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Dynamics of NLRP3, caspase-1, and IL-1β mRNA expression in cutaneous lesions in rabbits infected with T. pallidum. a Dynamics of NLRP3 mRNA in cutaneous lesions in rabbits infected with T. pallidum. b Dynamics of caspase-1 mRNA in cutaneous lesions in rabbits infected with T. pallidum. c Dynamics of IL-1β mRNA in cutaneous lesions in rabbits infected with T. pallidum. The arrow shows the time point of BPG treatment. Values represent the mean ± SD of triplicate experiments. A one-way analysis of variance was employed to examine the differences in the three groups, and Dunnett’s post-comparison test was used to conduct multiple comparisons. * P < 0.05, the BPG treatment subgroup or no BPG treatment subgroup vs. the blank group. # P < 0.05, the BPG treatment subgroup vs. the no BPG treatment subgroup