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. 2018 Feb 28;16:47. doi: 10.1186/s12967-018-1421-y

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The effect of Apatinib on intracellular signaling pathways was examined by CyTOF at the single-cell level in primary ALL. The primary ALL cells were exposed to 20 μM Apatinib for 48 h, and subjected to CyTOF analysis of intracellular signaling pathways downstream of VEGFR2